| Autor: |
Aurélie Najm, Benoît Le Goff, Carl Orr, Rogier Thurlings, Juan D. Cañete, Frances Humby, Stefano Alivernini, Antonio Manzo, Søren Andreas Just, Vasco C. Romão, Veit Krenn, Ulf Müller-Ladner, Olga Addimanda, Sander W. Tas, Maria Stoenoiu, Laurent Meric de Bellefon, Patrick Durez, Vibeke Strand, Mihir D. Wechalekar, Joao E. Fonseca, Bernard Lauwerys, Ursula Fearon, Douglas J. Veale, on behalf of EULAR Synovitis Study Group and OMERACT Synovial Tissue Special Interest Group |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-7 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
1478-6362 |
| DOI: |
10.1186/s13075-018-1762-1 |
| Popis: |
Abstract Background The aim of this global collaboration was to develop a consensual set of items for the analysis of synovial biopsies in clinical practice and translational research through the EULAR Synovitis Study Group (ESSG) and OMERACT Synovial Tissue Biopsy Group. Methods Participants were consulted through a modified Delphi method. Three sequential rounds occurred over 12 months. Members were sent a written questionnaire containing items divided into two parts. Items were identified and formulated based on a scoping review. The first part of the questionnaire referred to synovial biopsies in clinical practice including five subsections, and the second part to translational research with six subsections. Every participant was asked to score each item on a 5-point Likert scale. Items with a median score above 3.5 and a ≥ 70% agreement were selected for the next round. The last round was conducted orally at EULAR in June 2017. Results Twenty-seven participants from 19 centers were contacted by email. Twenty participants from 17 centers answered. Response rates for next rounds were 100%. For the first part relating to clinical practice, 20/44 items (45.5%) were selected. For the second part relating to translational research, 18/43 items (41.9%) were selected for the final set. Conclusions We herein propose a consensual set of analysis items to be used for synovial biopsies conducted in clinical practice and translational research. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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