A role for Separase in telomere protection

Autor: Francesca Cipressa, Patrizia Morciano, Giuseppe Bosso, Linda Mannini, Alessandra Galati, Grazia Daniela Raffa, Stefano Cacchione, Antonio Musio, Giovanni Cenci
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/ncomms10405
Popis: Drosophila telomeres are elongated by transposition of specialized retroelements rather than telomerase activity. Here, the authors show that Separase is enriched at Drosophila telomeres and loss of Sse, the gene encoding Separase, leads to telomere defects, suggesting a role for Separase in telomere protection.
Databáze: Directory of Open Access Journals