Evaluation of salivary opiorphin, pH and flow rate in oral submucous fibrosis - A case - Control observational study

Autor: K S Varsha, Krithika C Lakshmi, Anuradha Ganesan, A Kannan, K Yesoda Aniyan
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Pharmacy and Bioallied Sciences, Vol 15, Iss 5, Pp 656-660 (2023)
Druh dokumentu: article
ISSN: 0975-7406
DOI: 10.4103/jpbs.jpbs_15_23
Popis: Aim and Objectives: The aim of the study was to evaluate the salivary pH, flow rate and opiorphin in Oral submucous fibrosis patients and to compare them with healthy individuals. Materials and Methods: A comparative study was conducted to evaluate the salivary opiorphin levels, pH and flow rate among 78 patients (39 Oral submucous fibrosis + 39 control). Burning sensation was assessed using VAS score. Opiorphin levels were assessed using Cusabio Human Salivary Opiorphin ELISA kit. Salivary flow rate was assessed using graduated syringes and salivary pH was assessed using Hydrion salivary pH strips. Kolmogorov-Smirnov and Shapiro Wilk test were assessed for normality testing and distribution. Inferential statistics was done by using Unpaired t test/Independent sample t test to compare the mean values of variables included in the study among the OSMF and healthy patients. Results: There was statistically significant difference in pH and flow rate with a reduction in the mean pH (p=0.024) and flow rate (p
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