| Autor: |
Masashi Uchida, Natsumi Hanada, Shingo Yamazaki, Hirokazu Takatsuka, Chiaki Imai, Akari Utsumi, Yuki Shiko, Yohei Kawasaki, Takaaki Suzuki, Itsuko Ishii |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Journal of Pharmaceutical Health Care and Sciences, Vol 8, Iss 1, Pp 1-8 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2055-0294 |
| DOI: |
10.1186/s40780-021-00235-6 |
| Popis: |
Abstract Background The blood concentration of cyclosporine (CyA) is frequently elevated following the transfusion of red blood cell concentrate (RCC) to patients after allogeneic hematopoietic stem cell transplantation (HSCT). The aim of this retrospective study was to identify the variable factors affecting changes in the blood concentration of CyA before and after transfusion of RCC. Methods We enrolled 105 patients (age, 5–66 years) who received both CyA and transfusion after HSCT. The ratio of the measurement after transfusion to the measurement before transfusion was calculated for the hematocrit and blood concentration/dose ratio of CyA (termed the HCT ratio and the CyA ratio, respectively). Results The blood concentration/dose ratio of CyA was increased after transfusion compared with before transfusion (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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