Particular features of angiogenesis in lesions in patients suffering from basal cell epithelioma

Autor: A. N. Khlebnikova, N. V. Novoselova
Jazyk: English<br />Russian
Rok vydání: 2017
Předmět:
Zdroj: Vestnik Dermatologii i Venerologii, Vol 0, Iss 3, Pp 60-64 (2017)
Druh dokumentu: article
ISSN: 0042-4609
2313-6294
DOI: 10.25208/0042-4609-2014-0-3-60-64
Popis: Basal cell epithelioma is one of the most frequent malignant skin neoplasms. Angiogenesis plays an important part in the development of basal cell epithelioma. The article presents a review of the angiogenesis of this tumor with the help the immunohistochemistry analysis using CD31 and CD34 markers. The authors established a reliable relationship between the number of vessels expressing CD31 and those expressing CD34 in the superficial and nodular forms of the tumor as well as superficial, multi-center, nodular and infiltrative basal cell epitheliomas. A comparison of the number of vessels expressing CD31 and CD34 markers in different histological types made revealed a trend to their growth in the infiltrative type vs. superficial, multi-center and nodular ones.
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