| Autor: |
David F. Moreno, Cristina Jiménez, Fernando Escalante, Elham Askari, Marta Castellanos‐Alonso, Mario Arnao, Ángela Heredia, Miguel Á. Canales, Magdalena Alcalá, Arancha Bermúdez, Ana Saus Carreres, María Casanova, Luis Palomera, Cristina Motlló, Ricarda García‐Sánchez, Pablo Ríos Rull, Ramón García‐Sanz, Carlos Fernández de Larrea |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
HemaSphere, Vol 8, Iss 11, Pp n/a-n/a (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2572-9241 |
| DOI: |
10.1002/hem3.70029 |
| Popis: |
Abstract Asymptomatic IgM gammopathy encompasses IgM monoclonal gammopathy of undetermined significance (MGUS) and asymptomatic Waldenström macroglobulinemia (AWM), both having a risk of progression to symptomatic disease. Here, we assessed the risk of progression and the mortality of 956 patients with asymptomatic IgM gammopathy across 25 Spanish centers. After a median follow‐up of 5.7 years, 156 patients progressed, most of them to symptomatic WM (SWM). The cumulative incidence of progression was 13% and 20% at 5 and 10 years, respectively. The serum IgM ≥10 g/L, bone marrow (BM) infiltration ≥20%, β2‐microglobulin ≥3 mg/L, and albumin |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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