| Autor: |
David A McAllister, Firas S Ahmed, John H M Austin, Claudia I Henschke, Brad M Keller, Adina Lemeshow, Anthony P Reeves, Sonia Mesia-Vela, G D N Pearson, Maria C Shiau, Joseph E Schwartz, David F Yankelevitz, R Graham Barr |
| Jazyk: |
angličtina |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
PLoS ONE, Vol 9, Iss 4, p e93221 (2014) |
| Druh dokumentu: |
article |
| ISSN: |
1932-6203 |
| DOI: |
10.1371/journal.pone.0093221 |
| Popis: |
Emphysema on CT is common in older smokers. We hypothesised that emphysema on CT predicts acute episodes of care for chronic lower respiratory disease among older smokers.Participants in a lung cancer screening study age ≥ 60 years were recruited into a prospective cohort study in 2001-02. Two radiologists independently visually assessed the severity of emphysema as absent, mild, moderate or severe. Percent emphysema was defined as the proportion of voxels ≤ -910 Hounsfield Units. Participants completed a median of 5 visits over a median of 6 years of follow-up. The primary outcome was hospitalization, emergency room or urgent office visit for chronic lower respiratory disease. Spirometry was performed following ATS/ERS guidelines. Airflow obstruction was defined as FEV1/FVC ratio |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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