Noninvasive Assessment of Coronary Artery Disease: Fractional Flow Reserved Derived from Coronary Computed Tomography Angiography (FFRCT)

Autor: Rațiu Mihaela, Rat Nora, Condrea Sebastian, Stănescu Alexandra, Opincariu Diana, Mester András, Jani Laura, Benedek Imre, Benedek Theodora
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Journal of Interdisciplinary Medicine, Vol 1, Iss 2, Pp 137-141 (2016)
Druh dokumentu: article
ISSN: 2501-8132
DOI: 10.1515/jim-2016-0030
Popis: Invasive coronary angiography (ICA) completed by fractional flow reserve (FFR) assessment represents the main procedure that is performed in the decision process for coronary revascularization. Coronary Computed Tomography Angiography (CCTA) is an effective method used in the noninvasive anatomic assessment of coronary artery disease (CAD). However, CCTA tends to overestimate and does not offer hemodynamic data about the coronary lesions. Recent progresses made in the research involving computational fluid dynamics and image modeling permit the evaluation of FFRCT noninvasively, using data obtained in a standard CCTA. Studies have shown an improved precision and discrimination of FFRCT compared to CCTA for the diagnosis of significant coronary artery stenosis. In this review, we aimed to summarize the role of CCTA in CAD evaluation, the impact of FFRCT, the scientific basis of this novel method and its potential clinical applications.
Databáze: Directory of Open Access Journals