| Autor: |
Carolyn Marquis, Cindy L. Fonseca, Katelyn A. Queen, Lisa Wood, Sarah E. Vandal, Heidi L. H. Malaby, Joseph E. Clayton, Jason Stumpff |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-021-21447-2 |
| Popis: |
Kinesin motor proteins are critical for maintaining mitotic spindle integrity, which is important for chromosome stability. Here, the authors show that the kinesin motor protein, KIF18A, permits the proliferation of chromosomally unstable cells and knockdown of KIF18A induces centrosome fragmentation. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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