CMV and HSV-2 myeloradiculitis in an HIV infected patient
| Autor: | Adriana Pinto, Edwiges Santos, Danusa F. Correa, Rodrigo Escada, Carla de Mello Vorsatz, Sandra Wagner Cardoso, Marco A. Lima |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Revista do Instituto de Medicina Tropical de São Paulo, Vol 53, Iss 3, Pp 173-175 (2011) |
| Druh dokumentu: | article |
| ISSN: | 1678-9946 0036-4665 |
| DOI: | 10.1590/S0036-46652011000300010 |
| Popis: | While CMV myeloradiculitis is a known complication in AIDS patients with severe immunosuppression, HSV-2 necrotizing myeloradiculitis is rare and often associated with disabling a fatal outcome. We hereby describe a 46 year-old HIV infected patient with profound and sustained immunosuppression who presented with an acute ascending paraparesis and urinary retention. Lumbar spine MRI showed contrast enhancement at the conus medullaris and cauda equine, and both CMV and HSV-2 CSF PCR were positive. Despite treatment, the patient died 20 days later. We review the main diagnostic and therapeutic aspects of herpes virus associated myeloradiculitis and discuss the approach in similar cases. |
| Databáze: | Directory of Open Access Journals |
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