Improvement in sleep latency with extended-release once-nightly sodium oxybate for the treatment of adults with narcolepsy: Analysis from the phase 3 REST-ON clinical trial

Autor: Michael J. Thorpy, Clete A. Kushida, Richard Bogan, John Winkelman, Maurice M. Ohayon, Colin M. Shapiro, Jennifer Gudeman
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Sleep Medicine: X, Vol 7, Iss , Pp 100113- (2024)
Druh dokumentu: article
ISSN: 2590-1427
DOI: 10.1016/j.sleepx.2024.100113
Popis: Background: In the REST-ON clinical trial (NCT02720744), mean sleep latency on the Maintenance of Wakefulness Test (MWT) was significantly improved with extended-release once-nightly sodium oxybate (ON-SXB) vs placebo (P 10 % remained awake for the entirety of the MWT. ON-SXB offers a once-at-bedtime treatment option for adults with narcolepsy.
Databáze: Directory of Open Access Journals