Recent advances in the diagnosis and treatment of anti-neutrophil cytoplasmic antibody-associated vasculitis

Autor: Si-wei Tang, Ming Bai, Peng Zhang
Jazyk: čínština
Rok vydání: 2024
Předmět:
Zdroj: Linchuang shenzangbing zazhi, Vol 24, Iss 3, Pp 244-248 (2024)
Druh dokumentu: article
ISSN: 1671-2390
DOI: 10.3969/j.issn.1671-2390.2024.03.010
Popis: As a group of systemic autoimmune diseases, anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) is characterized by necrotizing inflammation and fibrinoid necrosis of small blood vessels in multiple systems and positive serum antibodies to anti-neutrophil cytoplasmic antibody. Renal injury is common in this disease. Major clinical manifestations are hematuria, proteinuria and varying degrees of renal impairment. Glucocorticoids plus immunosuppressive agents are a conventional treatment for AAV. However, this regimen has a high relapse rate and numerous adverse events. Seeking a safer, more effective and comprehensive treatment, this review summarized the latest advances in the diagnosis and treatment of AAV.
Databáze: Directory of Open Access Journals