Update on Intra-Arterial Chemotherapy for Retinoblastoma

Autor: Mario Zanaty, Guilherme Barros, Nohra Chalouhi, Robert M. Starke, Philip Manasseh, Stavropoula I. Tjoumakaris, Carol L. Shields, David Hasan, Ketan Bulsara, Robert H. Rosenwasser, Pascal Jabbour
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: The Scientific World Journal, Vol 2014 (2014)
Druh dokumentu: article
ISSN: 2356-6140
1537-744X
DOI: 10.1155/2014/869604
Popis: The tools for managing retinoblastoma have been increasing in the past decade. While globe-salvage still relies heavily on intravenous chemotherapy, tumors in advanced stage that failed chemotherapy are now referred for intra-arterial chemotherapy (IAC) to avoid enucleation. However, IAC still has many obstacles to overcome. We present an update on the indications, complications, limitations, success, and technical aspects of IAC. Given its safety and high efficacy, it is expected that IAC will replace conventional strategies and will become a first-line option even for tumors that are amenable for other strategies.
Databáze: Directory of Open Access Journals
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