| Autor: |
He Yilei, Yang Shuo, Ma Caihong, Yang Yan, Song Xueling, Zhang Jiajia, Liu Ping, Li Rong, Qiao Jie |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Frontiers in Surgery, Vol 9 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2296-875X |
| DOI: |
10.3389/fsurg.2022.1076889 |
| Popis: |
ObjectiveThe objective of the study was to investigate whether the sequence of oocyte retrieval and salpingectomy for hydrosalpinx affects pregnancy outcomes of in vitro fertilization and embryo transfer (IVF-ET) patients.Study DesignThere were 1,610 bilateral hydrosalpinx patients who underwent laparoscopy salpingectomy and IVF-ET/intracytoplasmic sperm injection (ICSI) from January 2009 to December 2018. They were divided into two groups: oocyte retrieval first group: 235 accepted oocyte retrieval before salpingectomy; operation first group: 1,375 accepted oocyte retrieval after salpingectomy. The basic information and pregnancy outcomes of the two groups were compared. The pregnancy outcomes and influencing factors were analyzed among patients at different starting times of frozen-thawed embryo transfer (FET) or oocyte retrieval after the salpingectomy.ResultsPatients in the oocyte retrieval first group had higher levels of basal follicle stimulating hormone and lower anti-Mullerian hormone levels (P 0.05). The live birth rates of patients ≥35 years old in the operation first group and the oocyte retrieval first group were not significantly different (29.3% vs. 23.3%, P = 0.240). After adjusting for age and antral follicle count (AFC), oocyte retrieval 4–6 and 7–12 months after the operation had higher accumulated pregnancy rates [OR 1.439 (1.045–1.982), P = 0.026; OR 1.509 (1.055–2.158), P = 0.024] and higher accumulated live birth rates [OR 1.419 (1.018–1.977), P = 0.039; OR 1.544 (1.068–2.230), P = 0.021]. No significant difference was observed in the pregnancy outcomes of frozen embryo transfer at different times after salpingectomy (P > 0.05).ConclusionNo contamination of the embryo or infection was observed in patients who underwent oocyte retrieval before the operation. The interval between the operation and frozen embryo transfer did not affect the pregnancy outcomes. After adjusting for age and AFC, patients who underwent oocyte retrieval 4–6 and 7–12 months after the operation had higher accumulated pregnancy rates and live birth rates. |
| Databáze: |
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| Externí odkaz: |
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