The basic science of bone marrow aspirate concentrate in chondral injuries

Autor: James Holton, Mohamed Imam, Jonathan Ward, Martyn Snow
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Orthopedic Reviews, Vol 8, Iss 3 (2016)
Druh dokumentu: article
ISSN: 2035-8237
2035-8164
DOI: 10.4081/or.2016.6659
Popis: There has been great interest in bone marrow aspirate concentrate (BMAC) as a cost effective method in delivering mesenchymal stem cells (MSCs) to aid in the repair and regeneration of cartilage defects. Alongside MSCs, BMAC contains a range of growth factors and cytokines to support cell growth following injury. However, there is paucity of information relating to the basic science underlying BMAC and its exact biological role in supporting the growth and regeneration of chondrocytes. The focus of this review is the basic science underlying BMAC in relation to chondral damage and regeneration.
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