The basic science of bone marrow aspirate concentrate in chondral injuries
Autor: | James Holton, Mohamed Imam, Jonathan Ward, Martyn Snow |
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Jazyk: | angličtina |
Rok vydání: | 2016 |
Předmět: | |
Zdroj: | Orthopedic Reviews, Vol 8, Iss 3 (2016) |
Druh dokumentu: | article |
ISSN: | 2035-8237 2035-8164 |
DOI: | 10.4081/or.2016.6659 |
Popis: | There has been great interest in bone marrow aspirate concentrate (BMAC) as a cost effective method in delivering mesenchymal stem cells (MSCs) to aid in the repair and regeneration of cartilage defects. Alongside MSCs, BMAC contains a range of growth factors and cytokines to support cell growth following injury. However, there is paucity of information relating to the basic science underlying BMAC and its exact biological role in supporting the growth and regeneration of chondrocytes. The focus of this review is the basic science underlying BMAC in relation to chondral damage and regeneration. |
Databáze: | Directory of Open Access Journals |
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