Expression spectrum of new circFBN1 in various tissues and follicles of Taihang chicken

Autor:	TENG-HE MA, MENG-XIAO LI, BEI-BEI ZHANG, XUE-NAN LI, JIA-RONG WEI, HONG-NA WANG, BIN WANG, YU-XIANG SHI
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Cell proliferation Chicken circFBN1 Granulosa cells Tissue expression Animal culture SF1-1100
Zdroj:	Indian Journal of Animal Sciences, Vol 92, Iss 11 (2022)
Druh dokumentu:	article
ISSN:	0367-8318 2394-3327
DOI:	10.56093/ijans.v92i11.127498
Popis:	In this study, the new circFBN1 derived from the FBN1 gene was identified. The expression spectrum of circFBN1 in various tissues and follicles of Taihang chickens was verified and analyzed. The effects on proliferation of GCs were checked. The results revealed that circFBN1 is indeed present and was differentially expressed in tissues and follicles and significantly promoted cell proliferation. In conclusion, our results suggested that circFBN1 could affect chicken follicular development by regulating the proliferation of GCs. These results will enable us recognize the molecular mechanisms in animal reproductive regulation.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/14de2b35fc2c47fa914d2e997786a6bf Zobrazit plný text záznamu View record in DOAJ