| Autor: |
Chyn Boon Wong, Toshitaka Odamaki, Jin-zhong Xiao |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Journal of Functional Foods, Vol 54, Iss , Pp 506-519 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
1756-4646 |
| DOI: |
10.1016/j.jff.2019.02.002 |
| Popis: |
Probiotics have shown great promise in promoting human health. Despite the promising evidence, there is little information on the clinical efficacy of many of the available probiotics and their mechanisms of action are often unclear. Bifidobacterium longum subsp. longum BB536 is a clinically effective, well-established, multifunctional probiotic that has a long history of human use in alleviating gastrointestinal, immunological and infectious diseases. This review summarizes the functional benefits of BB536 from the most relevant clinical and animal studies and offers a theoretical basis for understanding its mechanisms of action. Key clinical findings point out that BB536 could act as a microbiome modulator to orchestrate the physiological activities of gut communities. Specifically, BB536 modulates luminal metabolism, stabilizes gut microbiota, and ultimately drives a fine-tuned homeostatic balance within the host-microbiome interaction. Clinical evidence of effectiveness of BB536 and how such multifunctional activities take place would be valuable for an optimized probiotic selection. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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Full Text from ScienceDirect