Neurosarcoidosis Presentation as Adipsic Diabetes Insipidus Secondary to a Pituitary Stalk Lesion and Association with Anti-NMDA Receptor Antibodies

Autor: Jose Gabriel Solis, Arturo Olascoaga Lugo, Marco Antonio Rodríguez Florido, Bayron Alexander Sandoval Bonilla, Jose Malagón Rangel
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Case Reports in Neurological Medicine, Vol 2020 (2020)
Druh dokumentu: article
ISSN: 2090-6668
2090-6676
DOI: 10.1155/2020/7956350
Popis: Sarcoidosis is a multisystemic inflammatory disease of unknown cause. It is characterized by the presence of noncaseating granuloma on a biopsy specimen. Clinical presentation varies across case report series with myriad of symptoms ranging from fever, respiratory symptoms, and skin lesions, or atypical symptoms like heart block or neurological symptoms. Hence, we report the case of a 22-year-old woman with encephalitis, a pituitary mass, and adipsic diabetes insipidus. The diagnostic approach did not end on the biopsy of the lesion, which reported noncaseating granulomas; on the contrary, it was the beginning of a path to exclude other causes of the central nervous system granulomas that ended with the diagnosis of the isolated central nervous system sarcoidosis. Also, we report the first proven association between anti-NMDA receptor antibodies and sarcoidosis.
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje