Histological aspects of autologous transplantation of different fragments of the spleen in rats

Autor: Ana Abreu Braga, Rodolfo Malagó, Thiago Pires Anacleto, Cristiano Rodrigo Nicomedes da Silva, Nelson Adami Andreollo, Fabio Luis Figueiredo Fernandes
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Acta Cirúrgica Brasileira, Vol 27, Iss 12, Pp 880-884 (2012)
Druh dokumentu: article
ISSN: 0102-8650
Popis: PURPOSE: To evaluate macro and microscopically the evolution of autotransplants of fragments of spleen different fragments in the greater omentum, after eight weeks of observation. METHODS: Twenty rats Wistar were used, males and adults, submitted to total splenectomy and divided in two groups. The group I - ten animals with implant of spleen fragment (25% weight of spleen) in the omentum; and group II - ten animals with implant of spleen fragment (30% weight of spleen) in the omentum. It was analyzed macro and microscopically the evolution of the implant. RESULTS: It was observed adherences to the adjacent tissues and vascularization in all of the fragments transplanted. The group I and II presented white pulp with follicular formations and lymphoid tissue preserved, and the red pulp in cordon aspect. The group II presented white pulp more disorganized and red pulp hemorrhagic. The active macrophages were observed in the group I and II. CONCLUSION: The splenic autotransplantation of the group I showed better regeneration.
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