Fifteen-year experience of direct bridge with venoarterial extracorporeal membrane oxygenation to heart transplantationCentral MessagePerspective

Autor: Mojgan Laali, MD, PhD, Maharajah Ponnaiah, PhD, Guillaume Coutance, MD, PhD, Guillaume Hekimian, MD, Cosimo D'Alessandro, MD, Pierre Demondion, MD, Guillaume Lebreton, MD, PhD, Pascal Leprince, MD, PhD
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: JTCVS Open, Vol 22, Iss , Pp 286-303 (2024)
Druh dokumentu: article
ISSN: 2666-2736
DOI: 10.1016/j.xjon.2024.08.014
Popis: Objective: The study objective was to evaluate outcomes of patients directly bridged with venoarterial extracorporeal membrane oxygenation to heart transplantation. Methods: A single-center retrospective study was performed on 1152 adult patients undergoing isolated cardiac transplantation between January 2007 and December 2021. Among these, patients bridged with an extracorporeal membrane oxygenation to transplantation (extracorporeal membrane oxygenation group, n = 317) were compared with standard cohorts of patients (no extracorporeal membrane oxygenation group, n = 835). A period analysis (Era 1, 2007-2013, vs Era 2, 2014-2021) was performed. Results: Median duration of extracorporeal membrane oxygenation support before transplantation in the extracorporeal membrane oxygenation group was 8 days. Recipients of extracorporeal membrane oxygenation group were younger, with a better renal function and a shorter time on the waiting list. They were allocated to younger donors, with a longer ischemic time. The extracorporeal membrane oxygenation group and no extracorporeal membrane oxygenation group showed similar 1-year and 9-year survivals: 79.2% versus 79.4%, P = .98, and 56.2% versus 53.9%, P = .59, respectively. Period analysis in the extracorporeal membrane oxygenation group showed improved 1- and 9-year survivals in Era 2 compared with Era 1: 82.7% versus 71.1%, P = .021 and 60.4% versus 50.5%, P = .031, respectively. Era 2 was characterized by a higher rate of patients maintained on extracorporeal membrane oxygenation support after transplantation (92% vs 48%, P
Databáze: Directory of Open Access Journals