| Autor: |
Matthew L. Clarke, Charlotte E. S. Jones, Marcia B. France |
| Jazyk: |
angličtina |
| Rok vydání: |
2007 |
| Předmět: |
|
| Zdroj: |
Beilstein Journal of Organic Chemistry, Vol 3, Iss 1, p 24 (2007) |
| Druh dokumentu: |
article |
| ISSN: |
1860-5397 |
| DOI: |
10.1186/1860-5397-3-24 |
| Popis: |
Intramolecular carbonyl ene reactions of highly activated enophiles can be catalysed by H-bonding thio-ureas to give tertiary alcohols in high yields without extensive isomerisation side products. An asymmetric variant of this reaction was realised using a chiral thiourea but was limited by low enantioselectivity (up to 33% e.e.) and low turnover frequencies. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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