Autor: |
Kevin Bärlocher, Cedric A. J. Hutter, A. Leoni Swart, Bernhard Steiner, Amanda Welin, Michael Hohl, François Letourneur, Markus A. Seeger, Hubert Hilbi |
Jazyk: |
angličtina |
Rok vydání: |
2017 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-017-01512-5 |
Popis: |
Legionella pneumophila replicates in a Legionella-containing vacuole (LCV). Here the authors present the structure of the Legionella effector RidL N-terminal domain and reveal how RidL contributes to the subversion of retrograde trafficking by binding to the retromer coat complex subunit Vps29, which leads to a displacement of the regulator TBC1D5. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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