Effects of myocardial infarction and an intensive exercise bout on kinetic of lactate, and LDH-B levels in spontaneously hypertensive rats

Autor: Rafael Aguiar Marschner, Jocelito Bijoldo Martins, Melissa Medeiros Markoski, Alexandre Machado Lehnen, Maximiliano Isoppo Schaun
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Motriz: Revista de Educacao Fisica, Vol 26, Iss 1 (2020)
Druh dokumentu: article
ISSN: 1980-6574
24914975
DOI: 10.1590/s1980-6574202000010156
Popis: Abstract Aims: This study aimed to evaluate the kinetics of lactate and lactate dehydrogenase B (LDH-B) protein levels as well as the maximum effort capacity of spontaneously hypertensive rats (SHRs) with experimental acute myocardial infarction (AMI). Methods: thirty-two SHRs were divided into (n=8/group): S (sham), SE (sham+exercise), I (AMI), and IE (AMI+exercise). A maximum exercise test (treadmill) was evaluated before AMI or sham surgery. Echocardiography was performed 48h after the surgery. Lactacidemia was assessed at rest and during an intense exercise bout (48h after echocardiography). A two-way ANOVA followed by the post-hoc (Bonferroni) test was used, p
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