Autor: |
Jian-Feng Qu, Hui-Hong Hu, Jian-Fei Liu, Yue-Qiong Zhou, Wei-Yang Cheng, Lin Shi, Yi-Shan Luo, Lei Zhao, Yang-Kun Chen |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Předmět: |
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Zdroj: |
Frontiers in Aging Neuroscience, Vol 15 (2023) |
Druh dokumentu: |
article |
ISSN: |
1663-4365 |
DOI: |
10.3389/fnagi.2023.1259690 |
Popis: |
BackgroundChanges in social behavior can occur after ischemic stroke. We aimed to investigate the potential correlations between neuroimaging variables and changes in social behavior in patients who experienced subacute ischemic stroke.MethodsWe prospectively screened patients with first-ever ischemic stroke. Three months after the index stroke, changes in patients’ social behavior were investigated by the Frontal Behavioral Inventory (FBI), which consists of both deficit and positive groups of behaviors. The protocol of brain magnetic resonance imaging (MRI) including the baseline MRI at the acute stage and additional MRI with three-dimensional T1-weighted imaging on follow-up. Using these MRI scans, we assessed the acute infarction and the volumes of various brain structures by an automatic volumetry tool.ResultsEighty patients were enrolled. In univariate analyses, patients with deficit behavioral changes had more left cortical infarction (r = 0.271, p = 0.015), Cholinergic Pathways Hyperintensities Scale scores (r = 0.227, p = 0.042), DWMH volumes (r = 0.349, p = 0.001), and modified Rankin Scale (mRS) scores (r = 0.392, p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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