Transformation of pancreatic nonfunctioning neuroendocrine tumor into metastatic insulinoma: A rare case report

Autor: Venkata S. Buddhavarapu, Gagandeep Dhillon, Harpreet Singh Grewal, Brian Soles, Luke Halbur, Salim Surani, Rahul Kashyap
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Clinical Case Reports, Vol 11, Iss 11, Pp n/a-n/a (2023)
Druh dokumentu: article
ISSN: 2050-0904
DOI: 10.1002/ccr3.8152
Popis: Key Clinical Message Pancreatic neuroendocrine tumors can be classified as functional or nonfunctional based on hormone secretion. Management of each entity is different, with nonfunctional tumors being treated with traditional chemotherapy while functional tumors respond well to antihormonal therapy and immunologic agents. The conversion of one nonfunctional tumor into a functional tumor is an exceedingly rare event that complicates the overall management of these patients. In this report, we present the case of a 73‐year‐old woman who developed the conversion from a nonfunctional into a functional tumor and discuss the management options considered.
Databáze: Directory of Open Access Journals
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