A prospective, single centre, open label, single arm pilot study to evaluate the efficacy and safety of Amlapitta Mishran Suspension in participants with endoscopic gastritis

Autor: Yashashri C. Shetty, Paresh G. Koli, Manoj Lahoti, Savita Kulkarni, Preeti Rajput, Mukesh B. Chawda
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Ayurveda and Integrative Medicine, Vol 13, Iss 4, Pp 100664- (2022)
Druh dokumentu: article
ISSN: 0975-9476
DOI: 10.1016/j.jaim.2022.100664
Popis: Background: Endoscopic gastritis is associated with symptoms of gastritis, along with endoscopic findings. Amlapitta Mishran has multiple active components that act via various mechanisms in patients with gastritis symptoms. We planned to conduct this study to find out the efficacy and safety of Amlapitta Mishran in patients with endoscopic gastritis. Objectives: To find out efficacy of Amlapitta Mishran in patient with endoscopic gastritis. Materials and methods: This study was an open-label, prospective, single-center study. Thirty participants were recruited, and Amlapitta Mishran Suspension was given for 30 days. Blood investigations for safety were performed at baseline (Visit 1), on Visit 3 and Visit 4. Endoscopy was performed at baseline and Visit 4, and stomach erosion score was recorded. Amlapitta Symptom Rating Scale score, Postprandial Distress Syndrome (PPDS) score, and Epigastric Pain Syndrome (EPS) score were efficacy endpoints. Results: Out of the 30 participants recruited, 28 participants completed the study. The median age of participants in the study was 26.50 years. A statistically significant (P
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