| Autor: |
LIU Yuanfang, WANG Yan, SHI Xinming, XU Wenbin, WANG Xuefeng, MI Jianqing |
| Jazyk: |
čínština |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Zhenduanxue lilun yu shijian, Vol 22, Iss 02, Pp 172-177 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1671-2870 |
| DOI: |
10.16150/j.1671-2870.2023.02.011 |
| Popis: |
Objective: To explore whether the novel urine free light chain (uFLC) assay is superior to the traditional urine total light chain (uTLC) assay in quantitative monitoring of urine light chain. Methods: A total of 458 paired samples of blood and were collected from 280 patients (including 153 patients with plasma cell diseases and 137 patients with non-plasma cell diseases) from January 2022 to March 2023 at Ruijin Hospital， Shanghai Jiao Tong University School of Medicine. The positive concordance rates and correlations between the κ value, λ value and κ/λ ratio of uFLC and uTLC assays with the results of urinary immunofixation electrophoresis (uIFE) and serum free light chain (sFLC) were analyzed by Chi-squared test, MeNemar’s test and Spearman correlation coefficient calculation. Result: Among the 102 uIFE positive samples, 88.2% (90/102) of the samples had abnormal uFLC κ/λ ratio, and 87.3% (89/102) had abnormal uTLC κ/λ ratio (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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