Mortality, incidence, and microbiological documentation of ventilated acquired pneumonia (VAP) in critically ill patients with COVID-19 or influenza

Autor: Guillaume Laurichesse, Carole Schwebel, Niccolò Buetti, Mathilde Neuville, Shidasp Siami, Yves Cohen, Virginie Laurent, Bruno Mourvillier, Jean Reignier, Dany Goldgran‐Toledano, Stéphane Ruckly, Etienne de Montmollin, Bertrand Souweine, Jean‐François Timsit, Claire Dupuis, for the OUTCOME R. E. A. network
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Annals of Intensive Care, Vol 13, Iss 1, Pp 1-13 (2023)
Druh dokumentu: article
ISSN: 2110-5820
DOI: 10.1186/s13613-023-01207-9
Popis: Abstract Background Data on ventilator associated pneumonia (VAP) in COVID-19 and influenza patients admitted to intensive care units (ICU) are scarce. This study aimed to estimate day-60 mortality related to VAP in ICU patients ventilated for at least 48 h, either for COVID-19 or for influenza, and to describe the epidemiological characteristics in each group of VAP. Design Multicentre retrospective observational study. Setting Eleven ICUs of the French OutcomeRea™ network. Patients Patients treated with invasive mechanical ventilation (IMV) for at least 48 h for either COVID-19 or for flu. Results Of the 585 patients included, 503 had COVID-19 and 82 had influenza between January 2008 and June 2021. A total of 232 patients, 209 (41.6%) with COVID-19 and 23 (28%) with influenza, developed 375 VAP episodes. Among the COVID-19 and flu patients, VAP incidences for the first VAP episode were, respectively, 99.2 and 56.4 per 1000 IMV days (p
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