A rare case of asymptomatic giant pulmonary hamartoma

Autor: Xiaoming Fan, Barry Breaux, Laura Leonards, Rusella Mirza
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Diagnostic Pathology, Vol 19, Iss 1, Pp 1-5 (2024)
Druh dokumentu: article
ISSN: 1746-1596
DOI: 10.1186/s13000-024-01506-0
Popis: Abstract Background Pulmonary hamartomas are benign lung lesions. Histopathologically, pulmonary hamartoma is composed of varying amounts of mesenchymal elements, including chondroid tissue, mature adipose tissue, fibrous stroma, smooth muscle, and entrapped respiratory epithelium. Most pulmonary hamartoma cases are asymptomatic and found incidentally during imaging. They usually appear as well-circumscribed lesions with the largest dimension of less than 4 cm. Asymptomatic giant pulmonary hamartomas that more than 8 cm are rare. Case presentation In the current case report, a 12.0 × 9.5 × 7.5 cm lung mass was incidentally noticed in a 59-year-old female during a heart disease workup. Grossly, the lesion was lobulated with pearly white to tan-white solid cut surface and small cystic areas. Microscopically, representative tumor sections demonstrate a chondromyxoid appearance with relatively hypocellular stroma and entrapped respiratory epithelium at the periphery. No significant atypia is noted. No mitosis is noted, and the proliferative index is very low (
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