Comparative analysis of bone health and glycemic control in postmenopausal women: insights from clinical data

Autor: Adedeji D. Atere, Ebunoluwa O. Oyewole, Yekeen A. Kosamat, Gregory U. Joseph
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Bulletin of Faculty of Physical Therapy, Vol 29, Iss 1, Pp 1-6 (2024)
Druh dokumentu: article
ISSN: 2536-9660
DOI: 10.1186/s43161-024-00221-7
Popis: Abstract Background Menopause leads to significant physiological and biochemical alterations that impact different aspects of health, such as bone mineral metabolism and glycemic control. It is imperative to comprehend these alterations in order to identify potential health hazards and develop preventative measures. This comparative cross-sectional study aimed to evaluate bone-associated markers and glycemic control indices in postmenopausal women (PMP). Methods A sample of 100 women aged 30 years or older was randomly selected and categorized into three groups: PMP (n = 60), premenopausal (PRM) (n = 20), and women in the reproductive age group (RWA) (n = 20). Venous blood samples were collected, and fasting blood glucose (FBG), calcium, phosphorus, uric acid, and alkaline phosphatase (ALP) levels were analyzed using standard laboratory techniques. The insulin and estrogen levels were evaluated using enzyme-linked immunosorbent assay (ELISA), and Homeostasis model assessment of insulin resistance (HOMA-IR), Quantitative insulin sensitivity check index (QUICKI), and Fasting insulin resistance index (FIRI) were calculated. A significance level of p
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