Evidence of malarial chemoprophylaxis among travellers who died from malaria: a systematic review and meta-analysis

Autor: Manas Kotepui, Kwuntida Uthaisar Kotepui, Frederick Ramirez Masangkay, Polrat Wilairatana
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Malaria Journal, Vol 22, Iss 1, Pp 1-11 (2023)
Druh dokumentu: article
ISSN: 1475-2875
DOI: 10.1186/s12936-023-04794-x
Popis: Abstract Background Chemoprophylaxis is a prevention method for malaria during travel in malaria-endemic countries. This study aimed to collate and synthesize the evidence of malarial chemoprophylaxis among malaria death cases. Methods Studies documenting malarial chemoprophylaxis related to malaria deaths were searched in PubMed, Scopus, MEDLINE, Embase, and CENTRAL until 3 July 2022. The pooled proportion of malarial chemoprophylaxis among death cases was synthesized using logit transformation and back transformation to a proportion performed using generalized linear mixed models. The pooled log odds ratio (log-OR) with a 95% confidence interval (CI) of malarial chemoprophylaxis in death cases compared to survivors were synthesized. Results Fifty-eight studies were included in the systematic review and the meta-analysis. Of 602 pooled malaria death cases, the number of patients who took chemoprophylaxis was 187 (30%) (95% CI 22–40, P
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