A Giant Primary Mediastinal Teratocarcinoma in a Male Adult

Autor: Muneera Al-Khalifa, Sara Alsaad, Habib Al-Tareef, Zaid Arekat, Abdulla Darwish
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Case Reports in Surgery, Vol 2019 (2019)
Druh dokumentu: article
ISSN: 2090-6900
2090-6919
DOI: 10.1155/2019/7123241
Popis: Germ cell tumors (GCTs) arise along the midline, in which 50-70% of extragonadal GCTs occur in the mediastinum. Malignant GCTs are more common in males, while benign GCTs occur equally in both males and females. This report presents a case of a giant primary mediastinal nonseminomatous GCT resected from a 35-year-old male who presented with dyspnoea and tightness in the chest. Thorough investigations including a chest MRI were done. It showed a 21×19×15 cm tumor. Thus, surgical resection of the tumor through a midline sternotomy was done. Histopathological analysis diagnosed the tumor as a primary mediastinal teratocarcinoma with a sarcomatous component. Eighteen-month follow-up showed no tumor recurrence. Mediastinal teratocarcinoma is a rare and life-threatening germ cell tumor. Studies recommend the use of chemotherapy prior to resection as an important step in its management. Close and regular follow-up postsurgical resection is advised.
Databáze: Directory of Open Access Journals
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