Carbapenem resistant organisms: A 9-year surveillance and trends at Saint George University Medical Center

Autor: Amanda Chamieh, Gerard El-Hajj, Omar Zmerli, Claude Afif, Eid Azar
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Infection and Public Health, Vol 13, Iss 12, Pp 2101-2106 (2020)
Druh dokumentu: article
ISSN: 1876-0341
DOI: 10.1016/j.jiph.2019.02.019
Popis: Introduction: Carbapenem resistant organisms (CRO) constitute a large group of bacteria with different mechanisms of resistance and recently increasing global incidence. This rise has ambiguous dynamics and essential local epidemiologic data is lacking. Materials and methods: In this retrospective study at the 400-bed Saint George Hospital (SGH) in Beirut, Lebanon, we retrieved electronic laboratory records of all intrinsic and acquired CRO isolates from January 1, 2010 until June 30, 2018. Isolation density was calculated as: number of isolates/1000PD. Analysis carried out using WHOnet with a trend time series analysis. Results: During the study period, a total of 2150 non-duplicate CRO were isolated. While Acinetobacter baumanii (AB), Pseudomonas aeruginosa (CRPa), and Stenotrophomonas maltophilia (Sm) constituted 85% of total CRO in the study period, the carbapenem resistant enterobacteriaceae (CRE) rose from few sporadic cases before 2016 to a solid 32% of total CRO in 2018. Our most concrete trends were as follows. The rate of AB bacteremia was at an average of 0.114/1000 PD from 2011 to 2014. In 2015, a sudden doubling of AB bacteremia to 0.23/1000 PD. In 2017, there was a significant decrease to 0.113/1,000PD (p
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