| Autor: |
Chao Zhang, Chen Wang, Ruohua Yan, Xiaoxia Peng, Zimo Sun |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
BMJ Paediatrics Open, Vol 7, Iss 1 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2399-9772 |
| DOI: |
10.1136/bmjpo-2023-002132 |
| Popis: |
Background Several equations for glomerular filtration rate (GFR) estimation based on serum creatinine (SCr) have been proposed for children, but most were developed among patients with kidney disease. The association between SCr and GFR may be distorted by kidney dysfunction and thus not applicable to healthy children. This study aimed to evaluate the applicability of existing SCr-based GFR estimation equations in healthy Chinese children.Methods GFR estimation equations that developed in healthy children were mainly analysed, including the Flanders Metadata (FM), simple height-independent (Simple), full age spectrum (FAS) and FAS-height equations. The FM equation assumed that GFR is proportional to the ratio of height to SCr. The Simple, FAS and FAS-height equations assumed that the ratio of GFR to population mean is equal to the reciprocal ratio of SCr to population mean (denoted by Q). Estimated GFR were calculated using data of SCr, age, sex and height collected from 12 208 healthy Chinese children aged 3 months to |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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