Factor XI deficiency

Autor: Jayme Diamant, Adriana Regina Perez, Nydia Strachman Bacal, João Carlos de Campos Guerra, Eurípedes Ferreira
Jazyk: English<br />Portuguese
Rok vydání: 2004
Předmět:
Zdroj: Einstein (São Paulo), Vol 2, Iss 2, Pp 115-116 (2004)
Druh dokumentu: article
ISSN: 1679-4508
Popis: We describe a patient with a prolonged aPTT who was diagnosedas having factor XI deficiency after a rather large hematoma wasformed after angiography. Factor XI deficiency affects 1 in 1 millionpeople, but it is more common in Ashkenazim with a gene frequencyof 5% to 11%, being 0.3% homozygotes. These individuals usuallydo not present hemorrhagic events, except in cases of trauma orsurgery. These patients should be identified by routine coagulationscreening; bleeding could be prevented by use of fresh humanplasma or plasma concentrates.
Databáze: Directory of Open Access Journals