| Autor: |
Michelle Harriz Braga, Guilherme Grossi Lopes Cançado, Paulo Lisboa Bittencourt, Cláudia Alves Couto, Laura Vilar Guedes, André Mourão Costa Lima, Maria Lucia Gomes Ferraz, Cristiane Alves Villela-Nogueira, Jorge Nardelli Mateus, Luciana Costa Faria, Nathalia Mota De Faria Gomes, Maria Gomes Oliveira Elze, Vivian Rotman, Maria Beatriz Oliveira, Simone Muniz Carvalho Fernandes Cunha, Marlone Cunha-Silva, Liliana Sampaio Costa Mendes, Claudia Alexandra Pontes Ivantes, Liana Codes, Valéria Ferreira De Almeida Borges, Fabio Heleno De Lima Pace, Mario Guimarães Pessoa, Izabelle Venturini Signorelli, Gabriela Perdomo Coral, João Galizzi Filho, Aline Lopes Chagas, Debora Raquel Benedita Terrabuio, Eduardo Luiz Rachid Cançado |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Annals of Hepatology, Vol 28, Iss , Pp 101050- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1665-2681 |
| DOI: |
10.1016/j.aohep.2023.101050 |
| Popis: |
Introduction and Objectives: Primary biliary cholangitis (PBC) and autoimmune hepatitis (AIH) and PBC overlap syndrome (AIH/PBC) have been associated with a higher risk of hepatocellular carcinoma (HCC) and extra-hepatic malignancy (EHM). This study aimed to assess potential risk factors associated with cancer development in PBC and AIH/PBC patients. Materials and Methods: The Brazilian Cholestasis Study Group database was reviewed and analyzed. Results: Among the 752 PBC patients enrolled, 64 of them with AIH/PBC, and 87 cancers were identified in 79 patients, including 20 cases of HCC and 67 of EHM. Patients with HCC had a higher prevalence of cirrhosis (95% vs. 32.5%, p= |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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