Integrating Host Genomics with Surveillance for Invasive Bacterial Diseases

Autor: Dana C. Crawford, Shanta M. Zimmer, Craig A. Morin, Nancy E. Messonnier, Ruth Lynfield, Qian Yi, Cynthia Shephard, Michelle Wong, Mark J. Rieder, Robert J. Livingston, Deborah A. Nickerson, Cynthia G. Whitney, Jairam Lingappa
Jazyk: angličtina
Rok vydání: 2008
Předmět:
Zdroj: Emerging Infectious Diseases, Vol 14, Iss 7, Pp 1138-1140 (2008)
Druh dokumentu: article
ISSN: 1080-6040
1080-6059
DOI: 10.3201/eid1407.071287
Popis: We tested the feasibility of linking Active Bacterial Core surveillance, a prospective, population-based surveillance system for invasive bacterial disease, to a newborn dried blood spot (nDBS) repository. Using nDBS specimens, we resequenced CD46, putative host gene receptor for Neisseria meningitidis, and identified variants associated with susceptibility to this disease.
Databáze: Directory of Open Access Journals