Predictors of kidney function in a cohort of Mexican adults

Autor: Elva L Torrescano-de Labra, Lea A Cupul-Uicab, Paula Ramírez-Palacios, Jorge Salmerón, Carmen P Muñoz-Aguirre, Eduardo Salazar-Martínez
Jazyk: English<br />Spanish; Castilian
Rok vydání: 2020
Předmět:
Zdroj: Salud Pública de México, Vol 62, Iss 2, Mar-Abr, Pp 156-165 (2020)
Druh dokumentu: article
ISSN: 0036-3634
DOI: 10.21149/10615
Popis: Objectives. Our aim was to examine prospectively pre­dictors of subclinical renal alterations among adults without chronic kidney disease. Materials and methods. We analyzed data from a cohort of Mexican adults (n=757). Kidney function (2010) was assessed with the estimated glomerular filtration rate (eGFR-Cr), serum creatinine and uric acid. Predictors of each kidney function marker (2004) were identified with linear and logistic regression models. Results. 33% had an eGFR-Cr 40 years old and users of antihypertensive medication; and higher among those with a high protein intake. Serum creatinine predictors were similar to those observed for eGFR-Cr. Uric acid decreased in men, among those with obesity, hypertension and high cholesterol. Conclusion. Conventional kidney function biomarkers are useful to identify subclinical alterations. Some predictors of kidney function are potentially modifiable, therefore suscep­tible for intervention among high-risk groups.
Databáze: Directory of Open Access Journals