Progesterone-Mediated Enhancement of Hepatitis E Virus Replication in Human Liver Cells

Autor: Harini Sooryanarain, S. Ansar Ahmed, Xiang-Jin Meng
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: mBio, Vol 12, Iss 3 (2021)
Druh dokumentu: article
ISSN: 2150-7511
DOI: 10.1128/mBio.01434-21
Popis: Hepatitis E is usually a self-limiting acute disease; however, during pregnancy, a severe form of fulminant hepatic failure and high mortality rate are associated with hepatitis E virus (HEV) infection. Increased levels of progesterone and HEV RNA are observed in pregnant women with fulminant hepatic failures.
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