| Autor: |
Yang Liu, Xianwen Zhang, Jianying Liu, Hongjie Xia, Jing Zou, Antonio E. Muruato, Sivakumar Periasamy, Chaitanya Kurhade, Jessica A. Plante, Nathen E. Bopp, Birte Kalveram, Alexander Bukreyev, Ping Ren, Tian Wang, Vineet D. Menachery, Kenneth S. Plante, Xuping Xie, Scott C. Weaver, Pei-Yong Shi |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-022-31930-z |
| Popis: |
A live-attenuated COVID vaccine could enrich the current vaccine portfolio. Here, Liu et al. engineer a live-attenuated SARS-CoV-2 vaccine candidate by deleting four viral accessory genes and show immunogenicity and protection in mice and hamsters. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
Full text from SpringerLink