The relationship between circadian rhythm of blood pressure and vascular dysfunction in essential hypertension

Autor: Yancui Sun, Ying Zhang, Fei Liu, Xiaojie Liu, Tesfaldet H. Hidru, Xiaolei Yang, Yinong Jiang
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Clinical and Experimental Hypertension, Vol 45, Iss 1 (2023)
Druh dokumentu: article
ISSN: 1064-1963
1525-6006
10641963
DOI: 10.1080/10641963.2023.2229535
Popis: Objective This study aimed to explore whether circadian rhythm of blood pressure is associated with brachial-ankle pulse wave velocity (baPWV) and brachial artery flow-mediated dilation (FMD) in patients with essential hypertension. Method This cross-sectional study included 4,217 patients with essential hypertension who completed 24-hour ambulatory blood pressure monitoring, baPWV, and FMD. BaPWV and FMD were measured to evaluate arterial stiffness and endothelial dysfunction. Participants were divided into dipper, non-dipper, and reverse dipping groups according to the nocturnal systolic blood pressure dipping percentage. Results In this study, baPWV was highest in the reverse dipping groups, followed by non-dipper and dipper groups (1667.11 ± 327.90 vs. 1613.88 ± 325.11 vs. 1577.45 ± 306.15 cm/s, P
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