A Rare Case of Concurrent Lupus Mastitis and Sarcoidosis in a 62-Year-Old Female

Autor: Cheickna C. Fofana, Cinthia Del Toro, Jessica Alvarez-Lesmes, Cedric W. Pluguez-Turull
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: European Journal of Breast Health, Vol 20, Iss 3, Pp 228-230 (2024)
Druh dokumentu: article
ISSN: 2587-0831
DOI: 10.4274/ejbh.galenos.2024.2024-1-9
Popis: Systemic lupus erythematosus (SLE) and sarcoidosis are two of the most well-recognized, chronically diagnosed conditions in the United States, with a plethora of known multisystem manifestations. With regard to breast pathology, lupus mastitis is a relatively uncommon manifestation of SLE, commonly involving both the mammary gland and subcutaneous soft tissues of the breast. Sarcoidosis in the breast is a similarly, exceedingly rare manifestation of this multi-system disorder, classically presenting with non-caseating granulomas. Both present with non-specific mammographic and sonographic features. We present a 62-year-old female with known diagnosis of discoid lupus and Graves’ disease who presented initially with an abnormal screening mammogram, ultimately undergoing mammographic work-up and subsequent biopsy demonstrating lupus mastitis, including vasculitis, panniculitis, and fibrosis with chronic inflammation. The patient was also found to have small non-caseating granulomas, some in a perivascular distribution, classically seen in sarcoidosis. Given the rarity of both manifestations, our case explores the coexistence of these autoimmune processes and this atypical presentation.
Databáze: Directory of Open Access Journals
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