Oseltamivir-resistant influenza A(H1N1)pdm09 virus in southern Brazil
| Autor: | Camila Marx, Tatiana Schaffer Gregianini, Fernanda Kieling Moreira Lehmann, Vagner Ricardo Lunge, Silvia de Carli, Bibiana Paula Dambros, Gabriela Luchiari Tumioto, Claudete Seadi, Andre Salvador Kazantzi Fonseca, Nilo Ikuta |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Memorias do Instituto Oswaldo Cruz, Vol 108, Iss 3, Pp 392-394 (2013) |
| Druh dokumentu: | article |
| ISSN: | 1678-8060 0074-0276 |
| DOI: | 10.1590/S0074-02762013000300021 |
| Popis: | The neuraminidase (NA) genes of A(H1N1)pdm09 influenza virus isolates from 306 infected patients were analysed. The circulation of oseltamivir-resistant viruses in Brazil has not been reported previously. Clinical samples were collected in the state of Rio Grande do Sul (RS) from 2009-2011 and two NA inhibitor-resistant mutants were identified, one in 2009 (H275Y) and the other in 2011 (S247N). This study revealed a low prevalence of resistant viruses (0.8%) with no spread of the resistant mutants throughout RS. |
| Databáze: | Directory of Open Access Journals |
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