INTRA-ERYTHROCYTE INVASION OF ESCHERICHIA COLI STRAINS WITH VARIOUS LEVELS OF ANTIHEMOGLOBIN ACTIVITY IN EXPERIMENT
Autor: | E. A Schuplova, S. B Fadeev, O. V Bukharin |
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Jazyk: | ruština |
Rok vydání: | 2015 |
Předmět: | |
Zdroj: | Журнал микробиологии, эпидемиологии и иммунобиологии, Vol 92, Iss 4, Pp 40-44 (2015) |
Druh dokumentu: | article |
ISSN: | 0372-9311 2686-7613 |
Popis: | Aim. Study of intra-erythrocyte invasion of Escherichia coli strains with various levels of antihemoglobin activity on a model of generalized infection. Materials and methods. Experiments were carried out on 72 male mice. Generalized infection was induced by intravenous administration of E.coli strain day culture suspension with various values of hemolytic and antihemoglobin activity. The levels of hemoglobin in animal blood was determined by hemoglobin-cyanide method. Intra-erythrocyte invasion of E.coli was studied by using laser scanning confocal microscopy (LSCM). Results. The largest decline (p |
Databáze: | Directory of Open Access Journals |
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