| Autor: |
Gilvânia M. Santana, Anne K.S. Silva, Paula A.B. Ferreira, Stephen R. Benjamin, Erika K.G. Trindade, Rosa F. Dutra |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Sensing and Bio-Sensing Research, Vol 42, Iss , Pp 100594- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2214-1804 |
| DOI: |
10.1016/j.sbsr.2023.100594 |
| Popis: |
A new label-free immunosensor containing cetyltrimethylammonium bromide (CTAB) intercalated-graphene oxide (GO) on a polythiophene (PTh) film one-step electrosynthetized is described for detection of hepatitis C antibodies (Anti-HCV). This electroactive film also acted as a substrate for immobilizing the biorecognition element. The ability of the biosensor to bind Anti-HCV was monitored by the square wave voltammetry (SWV) technique through the decrease in anodic peaks. The intercalation of GO nanosheets between CTAB and PTh was very stable, achieving a variation coefficient of approximately 0.65% for redox peaks after 30 cycles, and was also demonstrated as a diffusion-controlled process with excellent electrochemical reversibility. The immunosensor exhibited a linear response range from 0.2 to 8 ng∙mL−1, good reproducibility (square R equal to 0.993, low relative error |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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