The Effects of Combined Exercise Training with Aerobic Dominant and Coenzyme Q10 Supplementation on Serum BDNF and NGF levels in Patients with Multiple Sclerosis
| Autor: | Javad Nakhzari Khodakheir, Amir Hossein Haghighi, Mohammad Reza Hamedinia |
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| Jazyk: | perština |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, Vol 21, Iss 3, Pp 94-103 (2018) |
| Druh dokumentu: | article |
| ISSN: | 1735-5338 2008-644X |
| Popis: | Background and Aim: Physical activity and exercise are as the methods stimulating the secretion of nerve growth factors in MS patients. Therefore, the purpose of this study was to investigate the effects of combined exercise training with aerobic dominant and supplementation of coenzyme Q10 on serum BDNF and NGF levels in patients with multiple sclerosis. Materials and Methods: In the semi-experimental research, twenty-eight MS patients (EDSS=3-5) were selected by using available sampling method and randomly divided into three experimental groups (combined exercise training + Q10 supplementation, combined exercise training + placebo, and Q10 supplementation) and one control group. two experimental groups performed a combined exercise program include two sessions of aerobic training and one session of resistance training three sessions per week for eight weeks. 200 mg of Q10 supplement was prescribed per day. Blood samples (after 10 hours fasting) were collected 24 hours before the first and 24 hours after the last session of exercise for evaluation of serum levels of BDNF and NGF. Data were analyzed with analysis of covariance at a significance level of p |
| Databáze: | Directory of Open Access Journals |
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