Effect of Taurine on Febrile Episodes in Acute Lymphoblastic Leukemia
| Autor: | Mina Islambulchilar, Iraj Asvadi, Zohreh Sanaat, Ali Esfahani, Mohammadreza Sattari |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Advanced Pharmaceutical Bulletin, Vol 5, Iss 1, Pp 103-108 (2015) |
| Druh dokumentu: | article |
| ISSN: | 2228-5881 2251-7308 |
| DOI: | 10.5681/apb.2015.014 |
| Popis: | Purpose: The purpose of our study was to evaluate the effect of oral taurine on the incidence of febrile episodes during chemotherapy in young adults with acute lymphoblastic leukemia. Methods: Forty young adults with acute lymphoblastic leukemia, at the beginning of maintenance course of their chemotherapy, were eligible for this study. The study population was randomized in a double blind manner to receive either taurine or placebo (2 gram per day orally). Life quality and side effects including febrile episodes were assessed using questionnaire. Data were analyzed using Pearson’s Chi square test. Results: Of total forty participants, 43.8% were female and 56.3 % were male. The mean age was 19.16±1.95 years (ranges: 16-23 years). The results indicated that the levels of white blood cells are significantly (P |
| Databáze: | Directory of Open Access Journals |
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