The correlations data between whether liposomes are coated or not and flatfish's (paralichthys olivaceus) Streptococcus parauberis antibody formation ability and survival rates

Autor: Eun Sol Jo, Hyun-Ja Han, Deok Chan Lee, Kwang Il Kim, Mi Young Cho, Sung-Hee Jung, Chan-Il Park, Andre Kim
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Data in Brief, Vol 25, Iss , Pp - (2019)
Druh dokumentu: article
ISSN: 2352-3409
DOI: 10.1016/j.dib.2019.104221
Popis: Streptococcus parauberis is a known etiologic agent that causes damage leading to death in flatfish (paralichthys olivaceus). Liposomes were used to deliver streptococcal oral vaccines to the intestinal mucous membranes of paralichthys olivaceus. The liposomes were coated for stabilization, and stability was measured with high performance liquid chromatography (HPLC). The liposomes were stable until day nine and were orally administered to flatfish as a vaccine. The resultant antibody titers were analyzed. The titers resulting from the uncoated liposomes were highest two weeks after the oral administration, and those resulting from the coated liposomes were highest one week after boosting. In addition, the bacteria were subcutaneously injected to artificially infect flatfish and the survival rates and relative survival rates were analyzed. The coated liposomes were found to yield the highest survival rate.
Databáze: Directory of Open Access Journals