Autor: |
Freddy Pessel, Jacques Augé, Isabelle Billault, Marie-Christine Scherrmann |
Jazyk: |
angličtina |
Rok vydání: |
2016 |
Předmět: |
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Zdroj: |
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 2351-2357 (2016) |
Druh dokumentu: |
article |
ISSN: |
1860-5397 |
DOI: |
10.3762/bjoc.12.228 |
Popis: |
Purification by flash chromatography strongly impacts the greenness of a process. Unfortunately, due to the lack of the relevant literature data, very often this impact cannot be assessed thus preventing the comparison of the environmental factors affecting the syntheses. We developed a simple mathematical approach to evaluate the minimum mass intensity of flash chromatography from the retention factor values determined by thin-layer chromatography. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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