Nanoplasmonic Strip Test for Salivary Glucose Monitoring

Autor: Helena Torné-Morató, Paolo Donati, Pier Paolo Pompa
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nanomaterials, Vol 12, Iss 1, p 105 (2021)
Druh dokumentu: article
ISSN: 2079-4991
DOI: 10.3390/nano12010105
Popis: Nowadays, there is an increasing interest in Point-of-care (POC) devices for the noninvasive glucose assessment. Despite the recent progress in glucose self-monitoring, commercially available devices still use invasive samples such as blood or interstitial fluids, and they are not equipment-free and affordable for the whole population. Here, we report a fully integrated strip test for the semi-quantitative detection of glucose in whole saliva. The colorimetric mechanism consists of an enzyme-mediated reshaping of multibranched gold nanoparticles (MGNPs) into nanospheres with an associated plasmonic shift and consequent blue-to-red color change, clearly detectable in less than 10 min.
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